Rouge Woman mostly resembled her organic form, though with obvious Robot Master qualities. Her head became helmet-like with her ears transforming into a pair of fins that rested on top of her head. Her muzzle became flattened, and her eyes became mechanical sensors with green irises on black "sclera." Her gloves and boots became part of her limbs, with her left arm transforming into the cannon from which she launched her black wave attack. She had white armor on her upper torso with a pink heart on the front, while her lower torso and upper legs were black like her organic self's outfit.
After Rouge went off to inspect the Wily Egg, she was captured and turned into Rouge Woman. Rouge Woman was then sent to stop Sonic the Hedgehog, Mega Man and their friends with the time-cloned Robot Masters. She proceeded to battle Knuckles before being de-roboticized by Mega Man and Rush.
- On the bottom of her feet are hearts unlike most of the Roboticized Masters who have circles on their feet. This could be because Rouge's actual design has hearts on her clothes.
- Rouge Woman is one the three female Roboticized Masters, the others being Rose Woman and Blaze Woman.
- In the concept artwork, Rouge Woman's eyes are red, while in the comic they're green.
- Rouge Woman fighting Knuckles is probably a nod to their rivalry in the games.