Mario and Sonic may refer to:
- Mario & Sonic series, a series of crossover video games starring these characters.
- Mario & Sonic at the Olympic Games, the first official crossover game between the two characters, released for the Wii and Nintendo DS.
- Mario & Sonic at the Olympic Winter Games, the second title in the Mario & Sonic series, released for the Wii and Nintendo DS.
- Mario & Sonic at the London 2012 Olympic Games, the third title in the Mario & Sonic series, released for the Wii.
- Mario & Sonic at the London 2012 Olympic Games (Nintendo 3DS), the third title in the Mario & Sonic series, released for the Nintendo 3DS.
- Mario & Sonic at the Sochi 2014 Olympic Winter Games, the fourth title in the Mario & Sonic series, released for the Wii U.
- Mario & Sonic at the Rio 2016 Olympic Games, the fifth title in the Mario & Sonic series, released for the Wii U.
- Mario & Sonic at the Rio 2016 Olympic Games (Nintendo 3DS), the fifth title in the Mario & Sonic series, released for the Nintendo 3DS.
- Mario & Sonic at the Rio 2016 Olympic Games Arcade Edition, the fifth title in the Mario & Sonic series, released in arcades.
- Mario & Sonic at the Olympic Games Tokyo 2020, the sixth and final title in the Mario & Sonic series, released for the Nintendo Switch.
- Mario & Sonic at the Olympic Games Tokyo 2020 - Arcade Edition, the sixth and final title in the Mario & Sonic series, released in arcades.