User blog comment:Rainbowroad6w/Sonic Generations coming to the Nintendo 3DS?/@comment-3990769-20110512224443/@comment-1986314-20110512235209

Yeah, having the 3D setting on only lasts 3 hours and can cause damage to the eyes, so it's best to keep the 3D settings low (It doesn't make much of a difference, from what I've heard).