Knuckles Clan (disambiguation)

Knuckles Clan may refer to:
 * Knuckles Clan, the group in the Sonic the Hedgehog video games.
 * Knuckles Clan (Archie), the group in the Sonic the Hedgehog comic series and its spin-offs published by Archie Comics.
 * Knuckles Clan (Pre-Super Genesis Wave), the version of the Knuckles Clan after the Super Genesis Wave.
 * Knuckles Clan (Sonic X), the group in the anime series Sonic X and its comic series published by Archie Comics.